DUAL-SIDED CENTRIPETAL MICROGROOVED POLY (D,L-LACTIDE-CO-CAPROLACTONE) DISK ENCASED IN IMMUNE-REGULATING HYDROGELS FOR ENHANCED BONE REGENERATION

Dual-sided centripetal microgrooved poly (D,L-lactide-co-caprolactone) disk encased in immune-regulating hydrogels for enhanced bone regeneration

Well-designed artificial scaffolds are urgently needed due to the limited self-repair capacity of bone, which hampers effective regeneration in critical defects.Optimal scaffolds must provide physical guidance to recruit cells Vase and immune regulation to improve the regenerative microenvironment.This study presents a novel scaffold composed of du

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Cognitive behavioural therapy versus supportive therapy for persistent positive symptoms in psychotic disorders: The POSITIVE Study, a multicenter, prospective, single-blind, randomised controlled clinical trial

Abstract Background It has been demonstrated that cognitive behavioural therapy (CBT) has a moderate effect on symptom reduction and on general well being of patients suffering from psychosis.However, questions regarding the specific efficacy of CBT, the treatment safety, the cost-effectiveness, and the Sold Out moderators and mediators of treatmen

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